About tMAVEN

tMAVEN is a program for analyzing time series data from single-molecule experiments. It is fine-tuned for single-molecule fluorescence resonance energy transfer (smFRET) experiments. The major design goals are to allow for:

• extremely fast pre-processing
• perfectly reproducible figures (e.g., tick locations)
• a one-stop-shop for kinetic modeling
• immutable data – you only work on a copy of it!
• power-user coding via scripts (see Examples pages)

Learn more

Check out the tMANUAL pages on this site, view some of the examples (links in the side bar), or join in on the discussions on Github

Who and Where

tMAVEN is a development that came out of the Gonzalez lab at Columbia University from about 2015-present.

Citing tMAVEN

If you use tMAVEN in your work, please cite the associated paper:

Verma, A.R., Ray, K., Bodick, M., Kinz-Thompson, C.D., Gonzalez, Jr., R.L. (2024) Increasing the accuracy of single-molecule data analysis using tMAVEN. Biophysical Journal. In press, DOI:10.1016/j.bpj.2024.01.022. bioRxiv Preprint: DOI:10.1101/2023.08.15.553409.